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Free-radical scavenging activity leaf extract of litsea laevigata gamble

By: Sujatha, S.
Contributor(s): Sekar, T.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2019Edition: Vol. 2(3).Description: 96-103p.Subject(s): PHARMACEUTICSOnline resources: Click here In: International journal of pharmacy and pharmaceutical scienceSummary: Objective: In the present study, antioxidant activity in the leaf of the pet -ether, chloroform, acetone and methanolic extracts from Litsea laevigata Gamble . Method s: The capability of the plant extract to act as hydrogen/electrons donor or scavenger of radicals were determined by Leaf was investigated by employing established in vitro studies. L. laevigata belongs to the Lauraceae family. in vitro antioxidant assays using 2,2 -diphenyl -2-picrylhydrazyl free radical (DPPH . ) scavenging , reducing power assay, superoxide radical (O 2 *- Result s: Results are evaluated higher in leaf extract of L. laevigata recorded total phenol , total flavonoid , and tannin. The present state of work was designed to evaluate the phytochemical, antioxidant in the plant leaf extracts of L. laevigata . The plant L. laevigata methanolic extract of leaf showed greater IC 50 antioxidant activity of DPPH assay ( 5.264 μg /ml ) and compare to other extract, higher ph osphomolybdenum reduction (164.36 mg/g) , better Reducing power activity leaf in methanol (0. 711% ), highe r ferric reducing power (4060.66 MmolFe(II)E/mg ), and higher in superoxide radi cal scavenging activity in (78.1 2 mg /ml ). However, the better metal chelating ability was shown by t he water extracts of the leaf (5.145 EDTAE/100g) compared to other solvent extrac
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Objective:
In the present study, antioxidant activity in the leaf
of the pet
-ether, chloroform, acetone and methanolic extracts from
Litsea laevigata
Gamble
.
Method
s:
The
capability
of the plant extract to act as hydrogen/electrons donor or scavenger of radicals were determined by
Leaf
was
investigated by employing established
in vitro
studies.
L. laevigata
belongs to the Lauraceae
family.
in vitro
antioxidant
assays using 2,2
-diphenyl
-2-picrylhydrazyl
free radical (DPPH
.
) scavenging
,
reducing power assay, superoxide radical (O
2
*-
Result
s:
Results are evaluated
higher in leaf extract
of
L. laevigata
recorded total phenol
, total flavonoid
, and
tannin.
The present state of work was
designed to evaluate the phytochemical, antioxidant
in the plant
leaf
extracts of
L.
laevigata
. The plant
L. laevigata
methanolic
extract of leaf showed
greater IC
50
antioxidant activity
of DPPH assay (
5.264
μg
/ml
) and compare to other extract, higher
ph
osphomolybdenum
reduction (164.36 mg/g)
,
better
Reducing power activity leaf
in methanol (0.
711%
), highe
r ferric reducing
power (4060.66
MmolFe(II)E/mg
), and higher
in superoxide
radi
cal scavenging activity in (78.1
2 mg
/ml
). However, the better metal chelating ability was shown by t
he water extracts of the
leaf
(5.145
EDTAE/100g) compared to other solvent extrac

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